Human Primary Cells

Cell models have been critical to enhancing our understanding of the biochemical, physiological, and genetic mechanisms underlying human disease and to developing therapeutic strategies. Primary cells are considered to be more biologically representative in comparison to cell lines owing to their very identical characteristics to the original donor tissue. Primary cell models are well-established, relatively easy and cheap to operate. The main advantage of this model is that it retains functions and phenotypes close to that of in vivo tissues/organs, and the effect of drugs/toxins can be investigated on isolated primary cells at the cellular level.