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Ozempic ( semaglutide) should stay refrigerated until the first time you use it You should keep it in the refrigerator (between 36°F to 46°F or 2°C to 8°C) when it’s new and unused After you’ve used your pen for the first time, you can either store your pen for 56 days at room temperature (between 59ºF to 86ºF or 15ºC to 30ºC) or Should I buy Ozempic online? 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